The Volokh Conspiracy

The Risks of Rejecting Vaccinations (Continued)

Glenn Reynolds has an uncharacteristically long post with additional perspective on the vaccination "controversy."

Steve Erickson (mail):
Some additional info can be found here, here, and here.
3.25.2008 8:26am
subpatre (mail):
GR quotes a doctor: “many pediatricians don't have time to waste in their very busy day discussing the "risks" of vaccinating one's children.” [scare quote original] who snarks that 10 minutes is far too long to waste on patients.

Fact: there are risks in vaccination. These are (often) the same pediatricians who decry firearms in homes, with a “risk factor” around 1:1million. Yet when it comes to medicine, they have no problem deliberately exposing your child to risks thousands of times greater . . . and then have the gall to claim it’s a waste of time to explain it to you.

Explain again why we ‘need’ to mandate Guardasil vaccine for our 7 year old girls.

I may not agree with non-vaccinators, but can fully understand their positions.
3.25.2008 8:41am
Nick P.:
Fact: there are risks in vaccination. These are (often) the same pediatricians who decry firearms in homes, with a “risk factor” around 1:1million. Yet when it comes to medicine, they have no problem deliberately exposing your child to risks thousands of times greater .

Which vaccine has a risk of serious side effects greater than 1/1000?
3.25.2008 8:51am
Steve Erickson (mail):
subpatre:

I agree with your point about firearms.

But your point about Guardasil is misplaced.

Cervical cancer is common and deadly. Moreover, since most cervical cancer is caused by human papillomavirus (HPV), it is preventable.

There might be some good libertarian arguments against compulsory vaccination; but it is also fair to say that parents who fail to get their children the Guardasil vaccine are very irresponsible.
3.25.2008 8:56am
FantasiaWHT:

That said, several years ago we say a world-wide polio outbreak that was traced to Nigeria. Muslim teachers told their people to refuse the vaccine. One or more of them went to Mecca, and suddenly we saw outbreaks throughout the Moslem world including countries that had been polio free for a decade or more.


Steve Erickson, the problem with your argument is that HPV is 100% preventable even WITHOUT the vaccine
3.25.2008 9:04am
FantasiaWHT:
Oops, forgot to comment on the block quote as well.

I was going to say that that story is really frightening, and underscores why we need to keep vaccinating against diseases which are supposedly eradicated.
3.25.2008 9:06am
Qwerty:
Glenn Reynolds has an uncharacteristically long post

But as usual, the Glenn Reynolds value added is negligible... quoting other people at length hardly counts as a "long Glenn Reynolds post".
3.25.2008 9:08am
Chukuang:
If seems that Malkin's real problem is with bad doctors, not vaccines per se. We encountered no resistance (so to speak) when my wife and I requested not to have our daughter vaccinated against the roto virus (we happily accepted all other vaccines, and it's more than a little frightening that Malkin is putting off the polio vaccine). At the same time, I think doctors DO have a responsibility to have that conversation with parents, even if it takes 10 minutes. She's right (and this is probably the first time I've said that about Malkin) that many things the medical establishment has said are gospel truth turn out to be completely wrong. That doesn't mean they are wrong about everything or even most things (and the evidences all says they are correct about vaccines in general), but it does mean that patients/parents have should feel free to ask for more information. Maybe if doctors consistently took more time to explain things like this, there wouldn't be quite so much anti-vaccine hysteria out there (though admittedly I think a lot of it has to do with other cultural factors).

Side note: it's interesting how fringe right conspiracy beliefs (fluoride, vaccines, pollution of previous bodily fluids in general) are now turning into fringe (and not so fringe) left beliefs.
3.25.2008 9:17am
alias:
I'm very happy to see that the "stuff white people like" blog is becoming popular enough that people can refer to it and expect others to know what they're talking about.
3.25.2008 9:26am
David Chesler (mail) (www):
How can someone out one side of the mouth say the risks of vaccination are so tiny, and out the other side call those who don't vaccinate free riders?

Dr. Schmidt, the pediatrician who doesn't have the time to discuss risks with parents, because he knows best, shows that dogmatic attitude Dr. Fleming recognizes: "Of course I know everything about the human body -- after all I created it on the sixth day, didn't I?"
3.25.2008 9:40am
DavidBernstein (mail):
Lots of things that are accepted in medicine are accepted without the type of scientific studies that would properly confirm that the general medical consensus is correct (see, e.g., the history of episiotomy). But unlike much of the "art" of medicine, vaccines do have real scientific studies showing their great benefits and minimal risks.
3.25.2008 9:55am
Blue (mail):
"How can someone out one side of the mouth say the risks of vaccination are so tiny, and out the other side call those who don't vaccinate free riders?"

Because it is, you know, TRUE. There is a non-zero risk and non-vaccinators do avoid it by relying on everyone else to take on that risk.

Incidently, one of the classic solutions to a free rider problem is to use social sanction to cow defectors into submission. Unfortunately with the Internets that is now more difficult since the free riders can get together and develop a mini-society of their own to resist this social sanction.
3.25.2008 10:03am
ScottVA:
Chukuang,

I could be wrong, but I read Malkin's post as commenting not on Polio vaccine, but on HepB?
3.25.2008 10:05am
bearing (mail) (www):
Still, though, you'd think 10 minutes discussing the risks is important.

I hope, for example, that the good doctor has time to ask if the child is allergic to eggs.
3.25.2008 10:05am
Chukuang:
ScottVA,

I was referring to the part where she writes: "I reiterated my refusal of Hep B, accepted DTaP and HiB, and asked to put off polio and Prevnar."

I assume she wasn't refusing it forever (and it seems she wouldn't object to even Hep B eventually), but I still think it's troubling to "put off" the polio vaccine.
3.25.2008 10:21am
Crackmonkeyjr (www):
Subpatre:

Would you suggest waiting until after girls are likely to already have HPV to vaccinate them against it?
3.25.2008 10:25am
Adam J:
David Chesler- please explain the contradiction... I don't see it.
3.25.2008 10:25am
David Chesler (mail) (www):
The contradiction is that the one hand is saying "The downsides of vaccination are so small as not to be worth discussing" while the other hand is saying "These non-vaccinators are free riders. We did our part by exposing ourselves to the downsides of vaccination; they are reaping the benefit without paying te same cost."

If the downsides are so small, the free rider issue doesn't make sense, because the paid-for riders haven't spent much either. If the paid-for riders have a valid complaint, we should be more willing to acknowledge and discuss the downside of vaccination.
3.25.2008 10:43am
Blue (mail):
"The downsides of vaccination are so small as not to be worth discussing."

But that's not what people are saying. The point is that any rational calculation at the societal level is massively, unambiguously, in favor of robust (and probably mandatory) vaccinations.
3.25.2008 10:46am
Elliot123 (mail):
"Steve Erickson, the problem with your argument is that HPV is 100% preventable even WITHOUT the vaccine"

Preventable by whom? Surely the daughter in question does not have the ability to make sure it is 100% prevented. She may be one of the minority of women that have only one partner in their entire lives, but she has no control over what that partner did prior to meeting her. Unless the guy was raised in a bubble, she assumes a risk that he has had one or more partners before her. And his partners had multiple partners.

Now, suppose the unvaccinated daughter is like the majority of women and has multiple partners in her life. As an unvaccinated and sexually active female, she poses a danger to the rest of the population.

And the parent? The parent has zero control.
3.25.2008 10:55am
Blue (mail):
Preventable in the same way that polio is "100 percent preventable" without a vaccine simply by ensuring that one never comes into contact with a carrier.

Not really a defensible position.
3.25.2008 10:57am
Chukuang:
...the problem with your argument is that HPV is 100% preventable even WITHOUT the vaccine

I assume you mean through abstinence. Yes, if a women never has sex during her lifetime (nor is raped or sexually abused) she is extremely unlikely to get HPV. So what? Car accidents are 100% avoidable by never coming near a car, does that mean seatbelts and airbags are unnecessary. Most women will have sex at some point in their lives, and they cannot count on 100% honesty from their partners, unfortunate though this latter fact is.
3.25.2008 11:07am
David Chesler (mail) (www):
CrackMonkeyJr - what is the benefit at all to Guardasil? Assume a prudent woman gets regular pap smears. What are the likely lifetime costs of an abnormal result, and how does being HPV-immune change that? What are the likely lifetime costs of early-detected cervical cancer? (Presumably HPV vaccination drops that by 70%, if the vaccine gives lifetime immunity.) Same question for later stages of cervical cancer.

Is there any cost to discussing "You might some day have unprotected sex with a man, even your future husband, who had had unprotected sex with someone who had HPV and being either uncircumcised or unlucky, carries it himself"?

Is there any cost besides cervical cancer in acquiring HPV?

If it's a public health/free rider issue, why aren't boys given the same vaccination? And why must patients or their insurers bear the costs of this and other vaccines? (Nobody but the patient can be immune, but the costs can very easily be spread across all who benefit.)

(Disclosures: That "I created remark" is from a cartoon several years ago, maybe Bizarro. I suggested my daughter receive the vaccination, the pediatrician and she concurred. Having dealt with real cancers my wife elected to have a contra-lateral mastectomy at the first sign of a 5mm DCIS, and in retrospect it didn't help, because the adriamycin [heart damage] and the same radiation that gave her increased risk for breast cancer [pneumonitis] killed her first -- anybody's call if the cost of the surgery was worthwhile: the breast reduction with extreme prejudice did relieve her TMJ and make her clothes fit better, she was easier to hug, and I've dealt with the "First He Cries" aspects here and here. On the other hand, my father chose the most minimal treatment for his prostate cancer 15 years ago, figuring something else would kill him first, and he was right: he died from a hemorrhagic stroke soon after the doctor increased his prophylactic coumadin dosage for 0.5 mg to 10.0 mg and his INR spiked over 9. Those deaths leave me finding peace in "When your time is up, your time is up" and being much less risk-averse.)
3.25.2008 11:12am
David Chesler (mail) (www):
Blue (first quoting me): "The downsides of vaccination are so small as not to be worth discussing."

But that's not what people are saying.


Dr. William Schmidt, commenting on Instapundit: And, in response to Michelle Malkin, many pediatricians don't have time to waste in their very busy day discussing the "risks" of vaccinating one's children. From personal experience, many parents, especially in the Google age, have just enough knowledge to turn this into a 5-10' conversation and will often continue to disagree with you afterwards. Ten minutes may not seem like much to the soccer mom who thinks that noted autism researcher Robert Kennedy is infallible, but it is to the pediatrician who would rather spend that time doing something more useful (like seeing another patient).
3.25.2008 11:17am
Blue (mail):
Again, that is not what Dr. Schmidt is saying. What he is saying is that, given the constraints on physician's day and the relative risk of vaccines, engaging in a probably ineffective conversation with a parent who will not listen to you in the first place is not a good use of his time.
3.25.2008 11:34am
autolykos:

Which vaccine has a risk of serious side effects greater than 1/1000?


The ones that cause autism. *ducks*
3.25.2008 11:42am
Elliot123 (mail):
Suppose a 14-year-old thinks his parents are nuts in their refusal to vaccinate him. He walks into a public health clinic. Can he get a vaccination without parental permission?
3.25.2008 11:45am
Elliot Reed (mail):
Yeah, even if she remains a lifelong virgin until marriage, a woman really cannot count on her (male) fiancé to have done the same, even if he claims to be a virgin. Men are under much stronger social pressures to have lots of sex than women are (a man who has sex with lots of partners is a stud, but a woman who does the same is a slut) in addition to having stronger sex drives, so men who tell their fiancées they're virgins can hardly be counted upon to be 100% truthful. Even men who remained virgins until their wedding night have been known to have affairs. Given the realities of rape and sexual assault, becoming a nun won't be 100% effective either: the only way to avoid STD's with certainty is suicide.
3.25.2008 11:48am
Roger Schlafly (www):
The risks of rejecting vaccinations is extremely low, no matter how you figure it. Going to Disneyland is probably riskier.
3.25.2008 12:26pm
J. F. Thomas (mail):
The risks of rejecting vaccinations is extremely low, no matter how you figure it. Going to Disneyland is probably riskier.

You just don't understand the free-rider concept do you? And how about tetanus? The risk of rejecting that vaccine is certainly not low.
3.25.2008 12:39pm
Mike Keenan:
We should applaud those doctors who advocate for the common good -- by insisting on vaccination (and not offering anti-biotics for every sore throat). Malkin was upset that she was threatened -- get the vaccine or leave. But, that seems to be a responsible position by the doctor. Follow my plan of care or find another doctor. Is that unreasonable?
3.25.2008 12:44pm
A.C.:
The HPV vaccination gets some strange reactions, doesn't it? But it's not really the same thing as the other diseases we vaccinate for, which spread in the air or by ordinary social contact. For the overwhelming majority of people, a disease that spreads that way is a much bigger risk than one that is spread by sex. The potential for contagion is much, much greater, and therefore the advantages of a herd immunity to the disease are higher.

I wouldn't try to talk anyone out of the HPV vaccine, but I'm solidly opposed to making it mandatory. The disease isn't going to sweep through institutions and shut them down, nor is it going to force parents to keep their kids at home all summer for fear of an epidemic. And while it's impossible to eliminate the risk of infection entirely, there are lots of things a prudent person can do to lower the risk and to deal with any consequences before they become lethal.

Perhaps people have forgotten what real epidemics are like, and what sort of problems the vaccination programs were designed to solve.
3.25.2008 12:45pm
Dan Weber (www):
Malkin was upset that she was threatened -- get the vaccine or leave. But, that seems to be a responsible position by the doctor. Follow my plan of care or find another doctor. Is that unreasonable?

That's an extremely rational reaction. The doctor should not be forced to provide care against his wishes.

I suspect that this will cause unvaccinated people to cluster to certain doctors. This clustering will probably not work out well for them when the inevitable diseases occur.
3.25.2008 12:52pm
kevin r (mail):
a woman really cannot count on her (male) fiancé to have done the same, even if he claims to be a virgin.


um. I know "men will lie to get sex!" makes for hilarious teen movies, but if you're *marrying* someone I'd hope you trust them more than that.
3.25.2008 1:14pm
theobromophile (www):
And how about tetanus? The risk of rejecting that vaccine is certainly not low.

For whom? When?

I think there's a lot to be said for mandating tetanus (and the boosters) for little kids. After all, someone who is watching out for their safety simply cannot know when they may have gotten exposed. You would hope that the kid would tell you about every scrape and encounter with a rusty nail, but that simply is not reality for little kids.

For adults? If you fall and hurt yourself, you can mosey into the doctor's office and get the vaccine. The fact that you may not be up-to-date on your booster shots does not mean that you'll get tetanus once exposed.

If it's a public health/free rider issue, why aren't boys given the same vaccination? And why must patients or their insurers bear the costs of this and other vaccines? (Nobody but the patient can be immune, but the costs can very easily be spread across all who benefit.)

Presumably, because the vaccine has yet to be tested and approved for boys. More than that, I could certainly see some people thinking that their boys aren't going to get cervical cancer, so why vaccinate them to the sole benefit of someone else?

As for women who may have unprotected sex with someone who is exposed - absolutely true. Then why not give it out at age 16, or let girls get it when they are of the age of majority, or otherwise make it available to those who are concerned, but not make it mandatory (as it is in 17 jurisdictions)? Is HPV not more like tetanus in that regard and less like, say, polio or pertussis?
3.25.2008 1:55pm
Elliot123 (mail):
"um. I know "men will lie to get sex!" makes for hilarious teen movies, but if you're *marrying* someone I'd hope you trust them more than that."

And it's that trust that entails risk.
3.25.2008 2:04pm
Elliot Reed (mail):
um. I know "men will lie to get sex!" makes for hilarious teen movies, but if you're *marrying* someone I'd hope you trust them more than that.
Oh, trust, but when you can't verify you sometimes run into problems. Such is reality.
3.25.2008 2:11pm
SeaDrive:
Some people seem to live a mythical world. "I'm not gonna give my daughter the vaccine 'cause she'll be a virgin" or "If you give girls the vaccine, they will be more likely to have sex." Get real. (The risk of HPV is so much less than the risk of HIV that it won't affect behavior.) The biggest effect of a program of taking HPV will be less cancer. Of course, you can be against that, if you like.

I'd be interested seeing a comparative analysis by the Freakonomics guys between voting behavior and vaccine acceptance. In each case, the probability effect on the individual is low, but the effect on the society is high.
3.25.2008 2:25pm
David Chesler (mail) (www):
I've been wondering the same thing about the comparison to voting. If everybody didn't vote would be one thing, but marginal votes rarely matter; same with vaccinations.
3.25.2008 2:30pm
JB:
As others have said re HPV vaccine:

If you think it's the risk of getting a virus that, in some decades, increases the risk of cancer, that's stopping your daughter from having sex, you're out of your mind.

The only effects of the HPV vaccine are (positive) reduced cancer risk, and (negative) whatever negative effects of vaccines in general. Waiting until she's no longer a virgin reduces the positive by the probability that her sexual partner is a carrier. There is absolutely nothing that adds to the negative.
3.25.2008 2:45pm
JDS:
Malkin actually is an interesting example. She objected to her child getting the HBV vaccine because, among other objections, she "tested negative."

Well, here one data point about her particular population: "In two population-based studies conducted among Asian/Pacific Islander children who were born in the United States before perinatal hepatitis B prevention programs were widely implemented, 61%--66% of the chronic HBV infections occurred in children born to HBsAg-negative mothers (72,73). A substantial proportion of these chronic infections would not have been prevented by a selective program of identification and immunization of only infants born to HBsAg-positive mothers."

My partner is a pediatrician, board certified in pediatrics, pediatric intensive care, and pediatric pulmonology. She works in a tertiary-care hospital, treating children with severe and chronic lung diseases. Every day she has to argue with parents who don't understand that the risks of vaccines (~1/1,000,000) are not worth argument time when weighed against the risk their children might die of vaccine-preventable diseases (~1/100).

Also, she treats immunocompromised kids who have been infected with vaccine-preventable disease -- because some [idiot] parent declined a safe vaccine.

If your child is being treated for leukemia, say, then a neighbor's kid with measles or chickenpox - possibly asymptomatic - is a mortal hazard.
3.25.2008 3:01pm
neurodoc:
theobromophile, I think we really owe it to the unwary to attach a warning label to your posts about vaccines, something like: "Listen to this ChemEngineer/law student/blogger about vaccines at your PERIL," with a skull and bones to make the point graphically. (see previous thread for our back and forth, with notable contributions by MDJD2B, on immunization practices).

Doctors in this country don't often see cases of tetanus, which are very instructive, especially for neurologists. So if anyone follows your advice and does come down with tetanus they will make excellent teaching material. We can use them to "pimp" the students on neurophysiology at the neuromuscular junction, asking them to compare and contrast tetanus with botulism and myasthenia gravis, extemporizing on channelopathies, talking about electrodiagnosis, etc.

It might be miserable, maybe fatal, for those who refuse tetanus boosters figuring they will just get wound care when they need it, but they will give us a teaching opportunity. (BTW, "boosters" are boosters, because they rely on previously established immunity and an anemnestic response to repeat challenges.)
3.25.2008 3:37pm
neurodoc:
JDS, really, what does your board certified in pediatrics, pediatric intensive care, and pediatric pulmonology partner know about these matter compared to those who have educated themselves through the Internet, filtering it all through "liberatarian" or "free thinking" minds know? The "wisdom" is to be found here, not emanating from those arrogant, authoritarian, conspiratorial, closed-minded medical types like your pediatrician partner. (Do I sound contemptuous? Yeah, I am, especially of those who should know better.)
3.25.2008 3:45pm
neurodoc:
JDS, really, what does your board certified in pediatrics, pediatric intensive care, and pediatric pulmonology partner know about these matter compared to those who have educated themselves through the Internet, filtering it all through "liberatarian" or "free thinking" minds know? The "wisdom" is to be found here, not emanating from those arrogant, authoritarian, conspiratorial, closed-minded medical types like your pediatrician partner. (Do I sound contemptuous? Yeah, I am, especially of those who should know better.)
3.25.2008 3:45pm
David Chesler (mail) (www):
It might be miserable, maybe fatal, for those who refuse tetanus boosters figuring they will just get wound care when they need it, but they will give us a teaching opportunity.

Well you've missed your chance with me. Every decade or so I come into an emergency department or urgent care facility with an animal bite or other nasty wound, and the conversation goes like this "When's the last time you had a tetanus booster?" "Ida know, 'bout 10 years ago maybe" "OK, turn around and drop your pants." (Last time they added "And mice don't get rabies.") I get annual physicals and see diabetes specialists more often, and I get all sorts of flu and pneumonia vaccines, but none have ever suggested I should get my tetanus shot then because it had been a while.
3.25.2008 3:48pm
David Chesler (mail) (www):
Me: If it's a public health/free rider issue, why aren't boys given the same vaccination?

Theobromophile: Presumably, because the vaccine has yet to be tested and approved for boys.

Is there any reason to think this perfectly save vaccine is more dangerous to boys than to girls?

More than that, I could certainly see some people thinking that their boys aren't going to get cervical cancer, so why vaccinate them to the sole benefit of someone else?

Isn't that what this whole discussion has been about, once we left child abuse, that vaccinations help others? And in this case that other is your future daughter-in-law, or at minimum someone who has shown your son a good time, rather than that neighbor kid with leukemia.
3.25.2008 3:54pm
David Chesler (mail) (www):
JB: If you think it's the risk of getting a virus that, in some decades, increases the risk of cancer, that's stopping your daughter from having sex, you're out of your mind.

What if you think giving a clear and consistent message not to have sex or do drugs, and to remain a child while a child, is better than giving a mixed message of "Don't have sex, but if you do, get Gardasil before you start and use a condom and don't get a reputation; and don't drink but if you do don't go to bed drunk unless you drink a lot of water and don't waste your money on cheap beer; and don't do drugs but here is how you roll a joint..."
3.25.2008 4:04pm
Daniel Chapman (mail):
My fiance's not at risk, especially not because she trusts me.
3.25.2008 4:14pm
Elliot123 (mail):
David,

Someone will step up to the plate and inform the kids about the protective steps they can take to avoid disease. That person may be the parent. If not it will be peers, teachers, doctors, nurses, internet, TV, movies, women's magazines, etc. I'd hope parents who choose to abstain from providing this information to their daughters would let them know medical professionals are the best people to consult for the information. They will get information somewhere; best they have correct information.
3.25.2008 4:20pm
David Chesler (mail) (www):
JDS: Every day she has to argue with parents who don't understand that the risks of vaccines (~1/1,000,000) are not worth argument time when weighed against the risk their children might die of vaccine-preventable diseases (~1/100).

Am I reading that right, that an unvaccinated American child stands a 1 in 100 chance of dying from a vaccine-preventable disease?

That "not worth argument time" is why people like chiropractors. (Although I wish my dentist talked to me less, given that I can't answer back.) Patient education is part of the job.
When my wife had her mastectomy she got proper, good education from her oncologist and her surgeon. A too-slick reconstructive surgeon sent his nurse into the exam room to pop in a videotape of a woman talking to her reconstructive surgeon. The nurse came back to ask if we had any questions, and we had just one: Where can we go to meet a surgeon like that, who explains things to his patients in person instead of showing them a movie?
3.25.2008 4:21pm
SeaDrive:

What if you think giving a clear and consistent message ...


A clear and consistent message about staying on the boat is not adequate justification for not wearing your life jacket.

Life is complex. Being simple-minded is not the best way to go.
3.25.2008 4:52pm
theobromophile (www):
Neurodoc, may I ask what your problem is?

Last time I went in for vaccines (before law school - needed Hep B to enroll), my doctor asked me when my last tetanus booster was. I had the exact same reaction as did David Chesler: "Er... five years ago? Ten years ago? How long does that thing last now?" I did not get the lecture from my doctor that you just gave to me; I think I just got a vaccine.

Now, if you would like to do the readers a favour, instead of insulting me, why not educate? Provide a few links about the risks of getting the tetanus vaccine upon exposure. Sure, it's harder than random snark, but it might prove educational to all involved. Until that happens, as there is not a vaccine against your cruelty, would you mind keeping it down to a dull roar?
3.25.2008 5:21pm
JB:
What if you think giving a clear and consistent message not to have sex or do drugs, and to remain a child while a child, is better than giving a mixed message of "Don't have sex, but if you do, get Gardasil before you start and use a condom and don't get a reputation; and don't drink but if you do don't go to bed drunk unless you drink a lot of water and don't waste your money on cheap beer; and don't do drugs but here is how you roll a joint..."

I think you (a) overestimate your ability to control your (hypothetical) child, and (b) are extremely bad at cost/benefit analysis.

Personally, I'd take the choice that lowers my (hypothetical) child's risk of a debilitating disease, and trust the rest of my parenting skills to stop her from having sex before she's ready.

Why do you want to give your (hypothetical) kid cancer?
3.25.2008 5:22pm
Frater Plotter:
Opposition to the HPV vaccine appears to be largely from people who believe that female sexual "misbehavior" should be punishable by a horrible death. Why don't these sickos just move to one of those countries where they stone adulteresses to death? Here in the West we believe in preventing disease, not using it as punishment.
3.25.2008 5:25pm
MDJD2B (mail):

Steve Erickson, the problem with your argument is that HPV is 100% preventable even WITHOUT the vaccine

By never gaving genital sex with ANYONE. There is no way to know that your partner is a virgin.
3.25.2008 5:52pm
MDJD2B (mail):

CrackMonkeyJr - what is the benefit at all to Guardasil? Assume a prudent woman gets regular pap smears. What are the likely lifetime costs of an abnormal result, and how does being HPV-immune change that? What are the likely lifetime costs of early-detected cervical cancer?

Avoiding painful biopsies, and conizations that can impede destroy the ability to have a baby. these procedures are used to treat the precancerous conditions that the Pap smear diagnoses.
3.25.2008 5:57pm
reformedliberal (mail):
Here's a quote of a quote from Instapundit:

"...many pediatricians don't have time to waste in their very busy day discussing the "risks" of vaccinating one's children."

Yeah... and then these same physicians wonder why people don't trust them. The pediatricians just expect parents to accept every word that comes out of their mouth as gospel, and anybody who asks a question out of turn is subjected to condescension and treated like a tinfoil hat-wearer.

Pediatricians, of all people, should recognize the need to educate parents, because after all the parents are the first line of defense when it comes to protecting a child's health.

Instead, we are subjected to the medical profession's systemic arrogance. Because, hey, they've NEVER been wrong about anything, right?
3.25.2008 6:38pm
theobromophile (www):
A few stats on tetanus, with love from the CDC:
Following the introduction and widespread use of tetanus toxoid vaccine in the United States, tetanus became uncommon. From 1947, when national reporting began, through 1998--2000, the incidence of reported cases declined from 3.9 to 0.16 cases per million population (96,97). Older adults have a disproportionate burden of illness from tetanus. During 1990--2001, a total of 534 cases of tetanus were reported; 301 (56%) cases occurred among adults aged 19--64 years and 201 (38%) among adults aged >65 years (CDC, unpublished data, 2005). Data from a national population-based serosurvey conducted in the United States during 1988--1994 indicated that the prevalence of immunity to tetanus, defined as a tetanus antitoxin concentration of >0.15 IU/mL, was >80% among adults aged 20--39 years and declined with increasing age. Forty-five percent of men and 21% of women aged >70 years had protective levels of antibody to tetanus (98). The low prevalence of immunity and high proportion of tetanus cases among older adults might be related to the high proportion of older adults, especially women, who never received a primary series (96,97).


Incidentally, unless you have a clean minor wound with vaccination between the last five and ten years (and appropriate childhood vaccinations), or you've been vaccinated within the last five years, you are supposed to head to the hospital to get a booster shot anyway.

Now, if that is incorrect, you can (kindly) provide better information. If not, doesn't that tell us that we ought to vigilently vaccinate children against tetanus (as I stated above), pregnant women (if not previously vaccinated), and ensure that adults understand that even up-to-date vaccines do not provide complete protection?

Oh, here's the warning sign for this comment. (Rolls eyes.)

---

David Chesler,

I have no idea why Gardasil was never tested on boys, nor why anyone would think it less effective and/or more dangerous [for those about to attack, "more" is a relative, not an absolute, term]; nevertheless, the FDA hasn't yet cleared it for boys.

As for preventing HPV transmission to one's lover: no complaints there. (I, however, am sufficiently old-fashioned as to believe that men owe women a duty to not transmit any STD to her - whether by vaccinating, getting fully tested, not sleeping around, or getting treatment for that which can be treated, or some combination of the above.)
3.25.2008 6:39pm
neurodoc:
Now, if you would like to do the readers a favour, instead of insulting me, why not educate? Provide a few links about the risks of getting the tetanus vaccine upon exposure.
The Td (tetanus and diphtheria booster immunization) you got probably carries a very, very small risk of a brachial plexopathy, and a rather doubtful one of Guillain-Barre Syndrome. (You haven't looked into these things before fulminating about the vaccines commonly administered to children and adults in this country?) If you check out the National Vaccine Injury Compensation Program's website, you will see that "brachial plexopathy" occuring within 30 days of receipt of a tetanus-toxoid-containing vaccine is treated as a "table injury," meaning that the petitioner seeking compensation from the trust fund administred by the government is entitled to the presumption that the vaccine caused the injury and does not have to prove causation-in-fact, which is often hard to do.

...instead of insulting me, why not educate? Sure, it's harder than random snark, but it might prove educational to all involved. Until that happens, as there is not a vaccine against your cruelty, would you mind keeping it down to a dull roar?
I have a rather high regard for your education and intelligence, so it has been disappointing, indeed dismaying, to see you going about "miseducating" others about vaccines and related health matters so energetically. Stop it and I will have no reason to be exasperated and serve up snark. (Please start by educating yourself as to why chicken pox is not the benign infectious disease you seem to think it is based on your personal experience of it as a child.)
3.25.2008 6:52pm
David Chesler (mail) (www):
I asked about cost-benefit for Gardisil, MDJD2B said Avoiding painful biopsies, and conizations that can impede destroy the ability to have a baby. these procedures are used to treat the precancerous conditions that the Pap smear diagnoses.

You can't do a cost-benefit like that. They say the HPV being vaccinated against is responsible for 70% of cervical cancer. Is it responsible for a comparable number of pre-cancerous signs? The individual must still get Pap smears, and is going to be have maybe 1/3 as many positives. What does that mean in actual numbers?

Theobromophile - I agree. A gentleman does not give a lady the clap.
3.25.2008 7:15pm
neurodoc:
There is no way to know that your partner is a virgin.
Understand that the person who said that has spent the majority of his years in two cities (LA and NYC) where virginity is not as highly prized, and thus may not be as common, as the "family valules" parts of this country. Also, he chose for himself a medical specialty, gynecologic oncology, that has exposed him to a great deal of human tragedy, some of it attributable to the choices women have made for themselves, but most of it bad luck or very bad luck. (He could have focused on OB, the specialty that gives the satisfaction of helping women deliver healthy babies.) He might know a thing or two about HPV, the HPV vaccine (Gardasil), cancer of the cervix, and related matters.

Is there any cost besides cervical cancer in acquiring HPV?
Yes, the human papilloma virus causes venereal warts (condyloma), which most people would prefer not to have. And babies born to women infected with HPV can acquire the infection, the resulting being warty growths in the upper respiratory tree (laryngeal papillomatosis), a rare, but horrendous, nigh unto impossible disease to treat. (No one covered this "background" stuff before proceeding to disparage the HPV vaccine, e.g., "HPV isn't going to reduce cervical cancer rates"?)
3.25.2008 7:19pm
Public_Defender (mail):
Our family doctor said that insurance is so low that she loses money on many vaccines in her small practice. That might account for why some doctors don't want to discuss the issue.

But it is inexcusable and thoroughly unprofessional for a doctor to be unwilling to take ten minutes to explain the costs and benefits of a drug. We chose our doctor because we trust her judgment and because she explains why she wants to do what she wants to do. Any doctor willing to take the 10 minutes should find another profession.

And yes, our doctor spent about ten minutes explaining the value of several childhood vaccines, and at the end of the ten minutes, we agreed. Ten minutes well spent.
3.25.2008 7:23pm
Tony Tutins (mail):
Life was certainly easier for doctors when they and the priests were the only educated people around, and the ordinary people, in awe, never questioned their superior knowledge and wisdom. Nowadays, any competent doctor should be ready to explain the pros and cons of different courses of treatment.
3.25.2008 7:39pm
Helen:
Gardasil will protect both males and females against genital warts caused by the HPV strains present in the vaccine. Vaccination of males will also prevent transmission of the HPV virus.

Right now, PAP smears are still recommended for patients who have received Gardasil, because it contains the four strains of the HPV virus responsible for most, but not all, cases of cervical cancer. When the next generation HPV vaccine, which includes additional viral strains, is available, PAP smears should no longer be necessary for female patients vaccinated before they were sexually active.
3.25.2008 8:17pm
MDJD2B (mail):

They say the HPV being vaccinated against is responsible for 70% of cervical cancer. Is it responsible for a comparable number of pre-cancerous signs?

Yes.
3.25.2008 8:57pm
SenatorX (mail):
Oops it looks like some of you aren’t so smart after all. Does it make you wonder what else you don't know? (I doubt it)

OHSU RESEARCH SUGGESTS AMERICA MAY OVER-VACCINATE

"The goal of this study was to determine how long immunity could be maintained after infection or vaccination. We expected to see long-lived immunity following a viral infection and relatively short-lived immunity after vaccination, especially since this is the reasoning for requiring booster vaccinations. Surprisingly, we found that immunity following vaccination with tetanus and diphtheria was much more long-lived than anyone realized and that antibody responses following viral infections were essentially maintained for life,” explained Mark Slifka, Ph.D."
3.25.2008 9:12pm
Public_Defender (mail):

Life was certainly easier for doctors when they and the priests were the only educated people around, and the ordinary people, in awe, never questioned their superior knowledge and wisdom. Nowadays, any competent doctor should be ready to explain the pros and cons of different courses of treatment.

Hey! Don't leave us lawyers off the list of learned but sometimes all-to-arrogant professions.
3.25.2008 9:13pm
Fub:
Public_Defender wrote at 3.25.2008 7:23pm:
But it is inexcusable and thoroughly unprofessional for a doctor to be unwilling to take ten minutes to explain the costs and benefits of a drug.
I've never understood why MDs don't have some boilerplate but detailed FAQs available about treatments that they commonly use. The ten minutes would be better spent answering any questions a patient has after reading the FAQ.

In non-emergency situations, and certainly in routine vaccination visits, there is no reason a patient shouldn't have the FAQ in hand to read weeks in advance of the office visit.
3.25.2008 9:37pm
Elliot123 (mail):
"I've never understood why MDs don't have some boilerplate but detailed FAQs available about treatments that they commonly use."

It would probably be used against them in a malpractice suit.
3.26.2008 12:23am
theobromophile (www):
Neurodoc, I think you are missing a part of the cost/benefit analysis - namely, the first element. As with all health care, there are financial costs, a possible cost in side effects, and other medical costs. When people ask about the former element and are only told, "Shut up, because the benefits are great," yes, we will complain - and we will complain loudly and stridently.

When those health procedures are made mandatory by the government, as a precondition to enrolling one's child in scohol, or, as in Maryland, upon threat of imprisonment, you ought to expect the public to look with a skeptical eye at both sides of the equation. When otherwise normal parents start to do things like forgo all vaccines for their children, including those for diseases which are deadly to pretty much everyone who gets them, not just a very unlucky, very small subset of the population, it might be time to examine the scope of the current vaccination procedures.

When those vaccines are pushed by pharmaceutical companies that have financed the campaigns of politicians who push them; stand to make billions annually (in America alone) from the vaccine; have tested the vaccine in clinical trials for two years before going to market and attempting to get mandates; and are looking to the vaccine to account for over 1/3d of its annual vaccine-related revenue, you damn well better expect that the complaints will reach a crescendo. That's not tin-foil-hat-wearing, scientific and/or medical ignorance, or anti-vaccine hysteria. It is citizens demanding that their children be treated as such, not as guinea pigs or cash cows. Part of that is to question, aggressively, the costs and benefits of the mandated vaccine(s).
3.26.2008 2:55am
theobromophile (www):
A P.S.:
have just enough knowledge to turn this into a 5-10' conversation and will often continue to disagree with you afterwards. Ten minutes may not seem like much to the soccer mom who thinks that noted autism researcher Robert Kennedy is infallible, but it is to the pediatrician who would rather spend that time doing something more useful (like seeing another patient).

Such crap. I've had doctors who have been able to explain - in under two minutes - the reasons for the treatment, lack of treatment (if such is the case), and proposed plan of attack. The ones who need 10 minutes are the ones who answer with, "Because I said so," or so equivalent thereof.

In the interests of saving time, I had one doctor who sent me home with a DVD about HBOC - hour-long, or so - along with various phone numbers, email addresses, and instructions to call if I had questions. That works. No need for her to give me an hour-long personal lecture. Physicians can certainly create these materials and give them to parents and/or patients; they can email them before the exam, in the case of vaccine materials, so the parents can arrive educated. What is totally unacceptable is to say, "I'm the one in the white coat; bow down, bow down."
3.26.2008 3:13am
Public_Defender (mail):

I've never understood why MDs don't have some boilerplate but detailed FAQs available about treatments that they commonly use. The ten minutes would be better spent answering any questions a patient has after reading the FAQ.

In non-emergency situations, and certainly in routine vaccination visits, there is no reason a patient shouldn't have the FAQ in hand to read weeks in advance of the office visit.

I agree. I would be grateful for that kind of information from my doctor. If they don't give us information they trust, they should expect us to either 1) show up with no knowledge and needing a complete explanation; or 2) have done research on the Internet and needing them to explain why I should not believe what I've read.
3.26.2008 7:08am
Elliot123 (mail):
"When otherwise normal parents start to do things like forgo all vaccines for their children, including those for diseases which are deadly to pretty much everyone who gets them, not just a very unlucky, very small subset of the population, it might be time to examine the scope of the current vaccination procedures."

I'd suggest it's time to examine if those parents really are otherwise normal.
3.26.2008 10:54am
Fub:
Public_Defender wrote at 3.26.2008 7:08am:
I agree. I would be grateful for that kind of information from my doctor. If they don't give us information they trust, they should expect us to either 1) show up with no knowledge and needing a complete explanation; or 2) have done research on the Internet and needing them to explain why I should not believe what I've read.
True story. Friend of mine was put on statins by his physician. He picked his physician as his family doc because he thought him sane and possessed of common sense.

My friend has an advanced degree in some arcane biomed area, genetic engineering or something like it, along with other scientific and technical degrees. He knows his way around medical research literature. He noticed some muscular soreness and weakness shortly into his statin regime.

Being a prudent patient, he researched for possible causes and cures of the symptoms. Yes, he used the internet. But he got citations for peer reviewed articles, obtained and read them. He decided it was intuitively obvious from the literature that his statin meds were inhibiting coenzyme Q10 synthesis. So, he went and bought a jar of CoQ10 supplements, began taking them regularly, and voila! The soreness and weakness went away.

He reported the symptoms, actions and results to his doc at his next checkup. Doc almost went ballistic, condescendingly told him that a placebo would probably work just as well, that laymen shouldn't believe everything they read on the internet, blah blah blah.

He pointed out to doc the peer reviewed literature. Doc repeated the rant, and added that he couldn't possibly understand medical literature because only physicians could do that, and in his professional opinion he just got lucky that his "research" didn't kill him. Doc finally conceded that taking CoQ10 supplements wouldn't do any harm, so he could continue if he found it "comforting".

Needless to say, one more reasonable and well educated person joined the "too many MDs are arrogant fools devoid of common sense" camp.
3.26.2008 12:13pm
neurodoc:
Fub, if your friend "noticed some muscular soreness and weakness shortly into his statin regime," the prudent thing for his doctor to do might have been to order blood work, specifically muscle enzymes, to be sure the statin drug was not posing a serious danger, notwithstanding the reported symptom relief with CoQ10 supplements.
3.27.2008 1:33am
Fub:
neurodoc wrote at 3.27.2008 1:33am:
Fub, if your friend "noticed some muscular soreness and weakness shortly into his statin regime," the prudent thing for his doctor to do might have been to order blood work, specifically muscle enzymes, to be sure the statin drug was not posing a serious danger, notwithstanding the reported symptom relief with CoQ10 supplements.
That may have been prudent, but instead he told the patient he was an idiot, and suggested that the relief was placebo effect. If ordering bloodwork would have been prudent, then not ordering bloodwork is also consistent with presuming that the symptoms were either imaginary or not indicative of a serious danger.

But neither you, nor I nor my friend the patient, can read the doc's mind. I only have his account of the event. He thought the doc was concerned with a perceived affront to his omniscience, not with the likelihood that the symptoms posed a serious danger. Your observation tends to support that by pointing out the dog that didn't bark.
3.27.2008 9:53am